Diarylthiazoles

TESTED COMPOUNDS 

Diarylthiazoles

INHIBITORY CONCENTRATION VALUES (MIC/IC50) 

MIC = 1 - 3 µM, 3 - 10 µM, > 10 µM

EXPERIMENTAL TECHNIQUE 

in vitro

LINK TO PUBMED 

https://pubmed.ncbi.nlm.nih.gov/32091697/

https://pubmed.ncbi.nlm.nih.gov/26883701/

2D STRUCTURE

2D Structure of Diarylthiazoles

MOLECULAR WEIGHT 

68995.625 Da

DRUG BANK ID 

https://go.drugbank.com/articles/A28368

REFERENCE 

Omansen, T. F., van der Werf, T. S., & Phillips, R. O. (2019). Antimicrobial Treatment of Mycobacterium ulcerans Infection. Buruli Ulcer: Mycobacterium ulcerans Disease, 203?220. https://doi.org/10.1007/978-3-030-11114-4_11

Scherr, N., Pluschke, G., & Panda, M. (2016). Comparative Study of Activities of a Diverse Set of Antimycobacterial Agents against Mycobacterium tuberculosis and Mycobacterium ulcerans. Antimicrobial Agents and Chemotherapy, 60(5), 3132?3137. https://doi.org/10.1128/AAC.02658-15