Azithromycin

EXPERIMENTAL DRUGS / POTENTIAL ANTIBIOTIC THERAPIES AGAINST M. ULCERANS

Azithromycin

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CLASS

Macrolide

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MECHANISM OF ACTION

Bacteriostatic activity

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DRUG INTERACTION PHASE (APPROVED, INVESTIGATIONAL, EXPERIMENTAL)

Investigational

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MODE OF ADMINISTRATION

Oral

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LINK TO PUBMED

https://pubmed.ncbi.nlm.nih.gov/32091697/                                                                                   

https://pubmed.ncbi.nlm.nih.gov/28392809/

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SIMILAR TARGETS IN OTHER SPECIES

23S ribosomal subunit ~ Enteric bacteria and other eubacteria

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DRUG BANK ID

DB00207

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EXTERNAL LINKS

Human Metabolome Database HMDB0014352

KEGG Compound C06838

PubChem Compound 447043

PubChem Substance 46507743

ChemSpider 10482163

BindingDB 50373918

RxNav 1299904

ChEBI 2955

ChEMBL CHEMBL529

ZINC ZINC000085537026

Drugs.com Drugs.com Drug Page https://www.drugs.com/cdi/azithromycin-drops.html

Wikipedia Azithromycin

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REFERENCE

Owusu, E., Newman, M. J., Addo, K. K., & Addo, P. (2017). In Vitro Susceptibility of Mycobacterium ulcerans Isolates to Selected Antimicrobials. The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses et de La Microbiologie Médicale, 2017. https://doi.org/10.1155/2017/5180984



Pluschke, G., & Röltgen, K. (2019). Buruli ulcer: Mycobacterium ulcerans disease. In Buruli Ulcer: Mycobacterium ulcerans Disease. https://doi.org/10.1007/978-3-030-11114-4

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