EXPERIMENTAL DRUGS / POTENTIAL ANTIBIOTIC THERAPIES AGAINST M. ULCERANS
Rifapentine
CLASS
Rifamycin
MECHANISM OF ACTION
Bactericidal activity
DRUG INTERACTION PHASE (APPROVED, INVESTIGATIONAL, EXPERIMENTAL)
Experimental
MODE OF ADMINISTRATION
Oral
LINK TO PUBMED
https://pubmed.ncbi.nlm.nih.gov/27755552/
SIMILAR TARGETS IN OTHER SPECIES
DNA-directed RNA polymerase subunit beta' ~ Mycobacterium tuberculosis
DRUG BANK ID
DB01201
EXTERNAL LINKS
Human Metabolome Database HMDB15332 KEGG Drug D00879 KEGG Compound C08059 PubChem Compound 6323497 PubChem Substance 46507322 ChemSpider 10482075 RxNav 35617 ChEBI 45304 ChEMBL CHEMBL1660 ZINC ZINC000169621228 Drugs.com Drugs.com Drug Page https://www.drugs.com/cdi/rifapentine.html Wikipedia Rifapentine
REFERENCE
Aure ?lie, C., Je ?ro?me, R., Nicolas, V., Alexandra, A., & Vincent, J. (2016). Sterilizing Activity of Fully Oral Intermittent Regimens against Mycobacterium ulcerans Infection in Mice. PLoS Neglected Tropical Diseases, 10(10). https://doi.org/10.1371/JOURNAL.PNTD.0005066