Ivermectins

EXPERIMENTAL DRUGS / POTENTIAL ANTIBIOTIC THERAPIES AGAINST M. ULCERANS

Ivermectins

---

CLASS

Avermectins

---

MECHANISM OF ACTION

Bactericidal activity ( Inhibits the growth and also kill Mycobacterium ulcerans strains)

---

DRUG INTERACTION PHASE (APPROVED, INVESTIGATIONAL, EXPERIMENTAL)

Experimental

---

MODE OF ADMINISTRATION

Oral

---

LINK TO PUBMED

https://pubmed.ncbi.nlm.nih.gov/25742173/

---

DRUG BANK ID

DB00602

---

EXTERNAL LINKS

Human Metabolome Database HMDB0014740

KEGG Drug D00804


PubChem Compound 46936176

PubChem Substance 46506810

ChemSpider 7988461

RxNav 6069

ChEMBL CHEMBL1200633

Drugs.com  Drugs.com Drug Page
https://www.drugs.com/cdi/ivermectin.htm

Wikipedia  Ivermectin

---

REFERENCE

Omansen F., O., Porter L., J., Johnson D.R., P., van der Werf, T. S., Stienstra, Y., & Stinear, T. P. (2015). In-vitro activity of avermectins against Mycobacterium ulcerans. PLoS Neglected Tropical Diseases, 9(3). https://doi.org/10.1371/JOURNAL.PNTD.0003549

---