EXPERIMENTAL DRUGS / POTENTIAL ANTIBIOTIC THERAPIES AGAINST M. ULCERANS
Ivermectins
CLASS
Avermectins
MECHANISM OF ACTION
Bactericidal activity ( Inhibits the growth and also kill Mycobacterium ulcerans strains)
DRUG INTERACTION PHASE (APPROVED, INVESTIGATIONAL, EXPERIMENTAL)
Experimental
MODE OF ADMINISTRATION
Oral
LINK TO PUBMED
https://pubmed.ncbi.nlm.nih.gov/25742173/
DRUG BANK ID
DB00602
EXTERNAL LINKS
Human Metabolome Database HMDB0014740
KEGG Drug D00804
PubChem Compound 46936176
PubChem Substance 46506810
ChemSpider 7988461
RxNav 6069
ChEMBL CHEMBL1200633
Drugs.com Drugs.com Drug Page
https://www.drugs.com/cdi/ivermectin.htm
Wikipedia Ivermectin
REFERENCE
Omansen F., O., Porter L., J., Johnson D.R., P., van der Werf, T. S., Stienstra, Y., & Stinear, T. P. (2015). In-vitro activity of avermectins against Mycobacterium ulcerans. PLoS Neglected Tropical Diseases, 9(3). https://doi.org/10.1371/JOURNAL.PNTD.0003549