EXPERIMENTAL DRUGS / POTENTIAL ANTIBIOTIC THERAPIES AGAINST M. ULCERANS
Epiroprim
MECHANISM OF ACTION
Bactericidal activity (inhibits dihydrofolate reductase)
DRUG INTERACTION PHASE (APPROVED, INVESTIGATIONAL, EXPERIMENTAL)
Experimental
MODE OF ADMINISTRATION
Injectable
LINK TO PUBMED
https://pubmed.ncbi.nlm.nih.gov/32091697/ https://pubmed.ncbi.nlm.nih.gov/11152437/
SIMILAR TARGETS IN OTHER SPECIES
Dihydrofolate reductase
EXTERNAL LINKS
PubChem Compound 68916
REFERENCE
Dhople M., A. (2001). Antimicrobial activities of dihydrofolate reductase inhibitors, used singly or in combination with dapsone, against Mycobacterium ulcerans. The Journal of Antimicrobial Chemotherapy, 47(1), 93?96. https://doi.org/10.1093/JAC/47.1.93