EXPERIMENTAL DRUGS / POTENTIAL ANTIBIOTIC THERAPIES AGAINST M. ULCERANS
Rifalazil
CLASS
Benzoxazinorifamycin
MECHANISM OF ACTION
Bactericidal activity
DRUG INTERACTION PHASE (APPROVED, INVESTIGATIONAL, EXPERIMENTAL)
Experimental
MODE OF ADMINISTRATION
Oral
LINK TO PUBMED
https://pubmed.ncbi.nlm.nih.gov/15211873/
SIMILAR TARGETS IN OTHER SPECIES
DNA-directed RNA polymerase subunit beta ~ Escherichia coli (strain K12)
DRUG BANK ID
DB04934
EXTERNAL LINKS
KEGG Drug D02550 PubChem Compound 6540558 PubChem Substance 175426909 ChemSpider 16736451 ChEMBL CHEMBL236297 ZINC ZINC000169677007 Wikipedia Rifalazil
REFERENCE
Nakanaga, K., Saito, H., Ishii, N., & Goto, M. (2021). [Comparison of inhibitory effect of rifalazil and rifampicin against Mycobacterium ulcerans infection induced in mice] - PubMed. https://pubmed.ncbi.nlm.nih.gov/15211873/