SPECIES
Holarrhena floribunda (G. Don) T. Durand et Schinz
FAMILY
Apocynaceae
COUNTRY OF COLLECTION
Ghana
COMMON /LOCAL NAMES
kpakpatoun
PART USED
Root
EXTRACTION METHOD
Maceration Liquid chromatography Fractionation
SOLVENT(S) USED
70% ethanol, Hexane,dichloromethane, ethyl acetate, and water (CH2Cl2 fractions) 70% ethanol, 2% sulfuric acid, hexane, 10% NaOH, dichloromethane(alkaloid enriched fraction extract)
SECONDARY METABOLITES / PHYTOCHEMICAL COMPOSITION
Saponins, polar steroidal glycosides, steroidal glycosides, alkaloids including holaphylline, holaphyllamine, holamine, holaphyllinol, holaphyllidine, holadysamine, holarrhesine, conessine, conanine, conamine, progesterone, norconessine (kurchine), conessimine, kurchamine, conimine, conamine, holarrhenine, holarrhimine, conarrhimine
ANTIMICROBIAL ASSAY METHODS
REMA
EXPERIMENTAL TECHNIQUE
in-vitro
ACTIVITY/MIC (µg/ml)
125 62.5
LINK TO REFERENCE
26779539
LINKS TO PLANT DATABASES
https://www.prota4u.org/database/protav8.asp?g=pe&p=Holarrhena+floribunda+(G.Don)+T.Durand+&+Schinz
REFERENCE
Tsouh Fokou, P. V., Nyarko, A. K., Appiah-Opong, R., Tchokouaha Yamthe, L. R., Ofosuhene, M., & Boyom, F. F. (2015). Update on Medicinal Plants with Potency on Mycobacterium ulcerans. BioMed Research International, 2015. https://doi.org/10.1155/2015/917086