SPECIES
Hydrastis canadensis L.
FAMILY
Ranunculaceae
COUNTRY OF COLLECTION
Ghana
PART USED
Root
EXTRACTION METHOD
Decoction
SOLVENT(S) USED
Water
SECONDARY METABOLITES / PHYTOCHEMICAL COMPOSITION
Alkaloids (major: hydrastine, berberine, canadine; minor: hydrastinine, canadaline, isohydrastidine, 1-β-hydrastine, 5-hydroxytetrahydroberberine, (S)-corypalmine, (S)-isocorypalmine, (S)-tetrahydropalmatine, Berberastine, 8-oxotetrahydrothalifendine, Canadinic acid), flavonoids (6,8-C-dimethylluteolin 7-methyl ether, 6-C-methylluteolin 7-methyl ether, sideroxylin, 8-desmethyl-sideroxylen, 6-desmethyl-sideroxylin), organic acids (quinic acid derivatives, hycandinic acid esters, 5-O-(4'-[β-d-glucopyranosyl]-trans-feruloyl) quinic), Sterols (β-sitosterol 3-O-β-D-glucoside), volatile oil, resin,and fatty acids
ANTIMICROBIAL ASSAY METHODS
Proportion method
EXPERIMENTAL TECHNIQUE
in-vitro
ACTIVITY/MIC (µg/ml)
0.39-6.25
LINK TO REFERENCE
26779539
LINKS TO PLANT DATABASES
https://www.gbif.org/species/3033110
REFERENCE
Tsouh Fokou, P. V., Nyarko, A. K., Appiah-Opong, R., Tchokouaha Yamthe, L. R., Ofosuhene, M., & Boyom, F. F. (2015). Update on Medicinal Plants with Potency on Mycobacterium ulcerans. BioMed Research International, 2015. https://doi.org/10.1155/2015/917086