Thiamine biosynthesis protein

GENE NAME

Thiamine biosynthesis protein

ORGANISM

Mycobacterium ulcerans (strain Agy99)

GENE NAME

thiC

GENE ID

4553301

TDR TARGET ID

952463

PROTEIN LENGTH

546

ASSOCIATED METABOLIC PATHWAYS

Thiamine metabolism

FUNCTION

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

UNIPROT ID

A0PTS1

STRING

362242.MUL_3600

KEGG PATHWAY

mul:MUL_3600

GO - MOLECULAR FUNCTION

GO:0051539

GO:0016830

GO:0008270

GO - BIOLOGICAL PROCESS

GO:0009228

GO:0009229

LINK TO PUBMED


REFERENCE

Butt, A. M., Nasrullah, I., Tahir, S., & Tong, Y. (2012). Comparative Genomics Analysis of Mycobacterium ulcerans for the Identification of Putative Essential Genesand Therapeutic Candidates.pdf (p. 16). https://doi.org/10.1371/annotation/8ce51727-91b0-463f-9b4c-768aab0a230a