Phosphoribosyl isomerase A

GENE NAME

Phosphoribosyl isomerase A

ORGANISM

Mycobacterium ulcerans (strain Agy99)

GENE NAME

hisA

GENE ID

4552312

TDR TARGET ID

953074

PROTEIN LENGTH

244

ASSOCIATED METABOLIC PATHWAYS

Histidine metabolism,Phenylalanine, tyrosine and tryptophan biosynthesis

FUNCTION

catalyzes the reversible transformation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate (CDRP) to 1-C-(indol-e-yl)-glycerol 3-phosphate (IGP), CO2 and H2O.

UNIPROT ID

A0PP18

STRING

362242.MUL_1591

KEGG PATHWAY

mul:MUL_1591

GO - MOLECULAR FUNCTION

GO:0004425

GO - BIOLOGICAL PROCESS

GO:0000162

LINK TO PUBMED


REFERENCE

Butt, A. M., Nasrullah, I., Tahir, S., & Tong, Y. (2012). Comparative Genomics Analysis of Mycobacterium ulcerans for the Identification of Putative Essential Genesand Therapeutic Candidates.pdf (p. 16). https://doi.org/10.1371/annotation/8ce51727-91b0-463f-9b4c-768aab0a230a