GENE NAME
ATP phosphoribosyltransferase
ORGANISM
Mycobacterium ulcerans (strain Agy99)
GENE NAME
hisG
GENE ID
4550462
TDR TARGET ID
954508
PROTEIN LENGTH
286
ASSOCIATED METABOLIC PATHWAYS
Histidine metabolism
FUNCTION
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
UNIPROT ID
A0PQU9
STRING
362242.MUL_2352
KEGG PATHWAY
mul:MUL_2352
GO - MOLECULAR FUNCTION
GO:0005524 GO:0003879 GO:0000287
GO - BIOLOGICAL PROCESS
GO:0000105
LINK TO PUBMED
https://pubmed.ncbi.nlm.nih.gov/22912793/
REFERENCE
Butt, A. M., Nasrullah, I., Tahir, S., & Tong, Y. (2012). Comparative Genomics Analysis of Mycobacterium ulcerans for the Identification of Putative Essential Genesand Therapeutic Candidates.pdf (p. 16). https://doi.org/10.1371/annotation/8ce51727-91b0-463f-9b4c-768aab0a230a