UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase (EC:6.3.2.13)

GENE NAME

UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase (EC:6.3.2.13)

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ORGANISM

Mycobacterium ulcerans (strain Agy99)

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GENE NAME

murE

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GENE ID

4550977

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TDR TARGET ID

952901

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PROTEIN LENGTH

559

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ASSOCIATED METABOLIC PATHWAYS

Lysine biosynthesis and Peptidoglycan biosynthesis

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FUNCTION

Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.

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UNIPROT ID

A0PTJ2

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STRING

362242.MUL_3506

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KEGG PATHWAY

mul:MUL_3506

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GO - MOLECULAR FUNCTION

GO:0005524

GO:0000287

GO:0008765

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GO - BIOLOGICAL PROCESS

GO:0007049

GO:0051301

GO:0071555

GO:0009252

GO:0008360

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LINK TO PUBMED

https://pubmed.ncbi.nlm.nih.gov/22912793/

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REFERENCE

Butt, A. M., Nasrullah, I., Tahir, S., & Tong, Y. (2012). Comparative Genomics Analysis of Mycobacterium ulcerans for the Identification of Putative Essential Genesand Therapeutic Candidates.pdf (p. 16). https://doi.org/10.1371/annotation/8ce51727-91b0-463f-9b4c-768aab0a230a

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