UDP-N-acetylmuramoylalaNyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase

GENE NAME

UDP-N-acetylmuramoylalaNyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase

ORGANISM

Mycobacterium ulcerans (strain Agy99)

GENE NAME

murF

GENE ID

TDR TARGET ID

PROTEIN LENGTH

ASSOCIATED METABOLIC PATHWAYS

Lysine biosynthesis and Peptidoglycan biosynthesis

FUNCTION

Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

UNIPROT ID

A0PTJ1

STRING

362242.MUL_3505

KEGG PATHWAY

mul:MUL_3505

GO - MOLECULAR FUNCTION

GO:0005524

GO:0008766

GO:0047480

GO - BIOLOGICAL PROCESS

GO:0007049

GO:0051301

GO:0071555

GO:0009252

GO:0008360

LINK TO PUBMED

https://pubmed.ncbi.nlm.nih.gov/22912793/

REFERENCE

Butt, A. M., Nasrullah, I., Tahir, S., & Tong, Y. (2012). Comparative Genomics Analysis of Mycobacterium ulcerans for the Identification of Putative Essential Genesand Therapeutic Candidates.pdf (p. 16). https://doi.org/10.1371/annotation/8ce51727-91b0-463f-9b4c-768aab0a230a