Aspartate kinase

GENE NAME

Aspartate kinase

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ORGANISM

Mycobacterium ulcerans (strain Agy99)

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GENE NAME

ask

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GENE ID

4551106

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TDR TARGET ID

954273

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PROTEIN LENGTH

421

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ASSOCIATED METABOLIC PATHWAYS

Glycine, serine and threonine  metabolism, Cysteine and methionine metabolism, Lysine biosynthesis

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FUNCTION

Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

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UNIPROT ID

A0PVE4

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STRING

362242.MUL_4297

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KEGG PATHWAY

mul:MUL_4297

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GO - MOLECULAR FUNCTION

GO:0004072

GO:0005524

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GO - BIOLOGICAL PROCESS

GO:0019877

GO:0009089

GO:0009088

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LINK TO PUBMED

https://pubmed.ncbi.nlm.nih.gov/22912793/

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REFERENCE

Butt, A. M., Nasrullah, I., Tahir, S., & Tong, Y. (2012). Comparative Genomics Analysis of Mycobacterium ulcerans for the Identification of Putative Essential Genesand Therapeutic Candidates.pdf (p. 16). https://doi.org/10.1371/annotation/8ce51727-91b0-463f-9b4c-768aab0a230a

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