GENE NAME
Fructose 1,6-bisphosphatase II
ORGANISM
Mycobacterium ulcerans (strain Agy99)
GENE NAME
glpX
GENE ID
4553973
TDR TARGET ID
952774
PROTEIN LENGTH
362
ASSOCIATED METABOLIC PATHWAYS
Glycolysis/Gluconeogenesis Pentose phosphate pathway , Fructose and mannose metabolism
FUNCTION
Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate (PubMed:15470127, PubMed:21451980). Seems to be the major FBPase of M. ulcerans and to play a key role in gluconeogenesis for conversion of lipid carbon into cell wall glycans
UNIPROT ID
A0PKR4
STRING
362242.MUL_0180
KEGG PATHWAY
mul:MUL_0180
GO - MOLECULAR FUNCTION
GO:0042132 GO:0046872
GO - BIOLOGICAL PROCESS
GO:0006094 GO:0006071
LINK TO PUBMED
https://pubmed.ncbi.nlm.nih.gov/22912793/
REFERENCE
Butt, A. M., Nasrullah, I., Tahir, S., & Tong, Y. (2012). Comparative Genomics Analysis of Mycobacterium ulcerans for the Identification of Putative Essential Genesand Therapeutic Candidates.pdf (p. 16). https://doi.org/10.1371/annotation/8ce51727-91b0-463f-9b4c-768aab0a230a