GENE NAME
1-deoxy-D-xylulose 5-phosphate reductoisomerase
ORGANISM
Mycobacterium ulcerans (strain Agy99)
GENE NAME
dxr
GENE ID
4551008
TDR TARGET ID
952059
PROTEIN LENGTH
402
ASSOCIATED METABOLIC PATHWAYS
Terpenoid backbone biosynthesis
FUNCTION
Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
UNIPROT ID
A0PQ95
STRING
362242.MUL_2085
KEGG PATHWAY
mul:MUL_2085
GO - MOLECULAR FUNCTION
GO:0030604 GO:0046872 GO:0070402
GO - BIOLOGICAL PROCESS
GO:0019288 GO:0016114
LINK TO PUBMED
https://pubmed.ncbi.nlm.nih.gov/22912793/
REFERENCE
Butt, A. M., Nasrullah, I., Tahir, S., & Tong, Y. (2012). Comparative Genomics Analysis of Mycobacterium ulcerans for the Identification of Putative Essential Genesand Therapeutic Candidates.pdf (p. 16). https://doi.org/10.1371/annotation/8ce51727-91b0-463f-9b4c-768aab0a230a