GENE NAME
Inorganic polyphosphate/ATP-NAD kinase
ORGANISM
Mycobacterium ulcerans (strain Agy99)
GENE NAME
ppnK
GENE ID
4551918
TDR TARGET ID
954860
PROTEIN LENGTH
307
ASSOCIATED METABOLIC PATHWAYS
Nicotinate and Nicotinamide metabolism
FUNCTION
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
UNIPROT ID
A0PPA4
STRING
362242.MUL_1684
KEGG PATHWAY
mul:MUL_1684
GO - MOLECULAR FUNCTION
GO:0005524 GO:0046872 GO:0003951
GO - BIOLOGICAL PROCESS
GO:0019674 GO:0006741
LINK TO PUBMED
https://pubmed.ncbi.nlm.nih.gov/22912793/
REFERENCE
Butt, A. M., Nasrullah, I., Tahir, S., & Tong, Y. (2012). Comparative Genomics Analysis of Mycobacterium ulcerans for the Identification of Putative Essential Genesand Therapeutic Candidates.pdf (p. 16). https://doi.org/10.1371/annotation/8ce51727-91b0-463f-9b4c-768aab0a230a