GENE NAME
Two component sensor histidine kinase
ORGANISM
Mycobacterium ulcerans (strain Agy99)
GENE NAME
devS
GENE ID
4550363
TDR TARGET ID
955652
PROTEIN LENGTH
585
ASSOCIATED METABOLIC PATHWAYS
Two-component system
FUNCTION
The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.
UNIPROT ID
A0PR05
STRING
362242.MUL_2422
KEGG PATHWAY
mul:MUL_2422
GO - MOLECULAR FUNCTION
GO:0000155 GO:0046983
LINK TO PUBMED
https://pubmed.ncbi.nlm.nih.gov/22912793/
REFERENCE
Butt, A. M., Nasrullah, I., Tahir, S., & Tong, Y. (2012). Comparative Genomics Analysis of Mycobacterium ulcerans for the Identification of Putative Essential Genesand Therapeutic Candidates.pdf (p. 16). https://doi.org/10.1371/annotation/8ce51727-91b0-463f-9b4c-768aab0a230a