GENE NAME
ATP-dependent DNA helicase
ORGANISM
Mycobacterium ulcerans (strain Agy99)
GENE NAME
recG
GENE ID
4551166
TDR TARGET ID
951514
PROTEIN LENGTH
743
ASSOCIATED METABOLIC PATHWAYS
Homologous recombination
FUNCTION
Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).
UNIPROT ID
A0PQ10
STRING
362242.MUL_1985
KEGG PATHWAY
mul:MUL_1985
GO - MOLECULAR FUNCTION
GO:0005524 GO:0016887 GO:0003678 GO:0003676
GO - BIOLOGICAL PROCESS
GO:0006310 GO:0006281
LINK TO PUBMED
https://pubmed.ncbi.nlm.nih.gov/22912793/
REFERENCE
Butt, A. M., Nasrullah, I., Tahir, S., & Tong, Y. (2012). Comparative Genomics Analysis of Mycobacterium ulcerans for the Identification of Putative Essential Genesand Therapeutic Candidates.pdf (p. 16). https://doi.org/10.1371/annotation/8ce51727-91b0-463f-9b4c-768aab0a230a