GENE NAME
Preprotein translocase subunit
ORGANISM
Mycobacterium ulcerans (strain Agy99)
GENE NAME
secA1
GENE ID
4550029
TDR TARGET ID
952820
PROTEIN LENGTH
950
ASSOCIATED METABOLIC PATHWAYS
Protein export and Bacterial secretion system
FUNCTION
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
UNIPROT ID
A0PRE5
STRING
362242.MUL_2576
KEGG PATHWAY
mul:MUL_2576
GO - MOLECULAR FUNCTION
GO:0005524 GO:0008564
GO - BIOLOGICAL PROCESS
GO:0065002 GO:0017038 GO:0006605
LINK TO PUBMED
https://pubmed.ncbi.nlm.nih.gov/22912793/
REFERENCE
Butt, A. M., Nasrullah, I., Tahir, S., & Tong, Y. (2012). Comparative Genomics Analysis of Mycobacterium ulcerans for the Identification of Putative Essential Genesand Therapeutic Candidates.pdf (p. 16). https://doi.org/10.1371/annotation/8ce51727-91b0-463f-9b4c-768aab0a230a