4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase

GENE NAME

4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase

ORGANISM

Mycobacterium ulcerans (strain Agy99)

GENE NAME

ispG

GENE ID

4551010

TDR TARGET ID

951729

PROTEIN LENGTH

363

ASSOCIATED METABOLIC PATHWAYS

Terpenoid backbone biosynthesis

FUNCTION

Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

UNIPROT ID

A0PQ97

STRING

362242.MUL_2087

KEGG PATHWAY

mul:MUL_2087

GO - MOLECULAR FUNCTION

GO:0046429

GO:0051539

GO:0005506

GO - BIOLOGICAL PROCESS

GO:0019288

GO:0016114

LINK TO PUBMED


REFERENCE

Butt, A. M., Nasrullah, I., Tahir, S., & Tong, Y. (2012). Comparative Genomics Analysis of Mycobacterium ulcerans for the Identification of Putative Essential Genesand Therapeutic Candidates.pdf (p. 16). https://doi.org/10.1371/annotation/8ce51727-91b0-463f-9b4c-768aab0a230a