Dihydropteroate synthase 2

GENE NAME

Dihydropteroate synthase 2

ORGANISM

Mycobacterium ulcerans (strain Agy99)

GENE NAME

folP2

GENE ID

4552207

TDR TARGET ID

955665

PROTEIN LENGTH

291

ASSOCIATED METABOLIC PATHWAYS

Folate biosynthesis

FUNCTION

Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

UNIPROT ID

A0PML1

STRING

362242.MUL_0958

KEGG PATHWAY

mul:MUL_0958

GO - MOLECULAR FUNCTION

GO:0004156

GO:0046872

GO - BIOLOGICAL PROCESS

GO:0046656

GO:0046654

LINK TO PUBMED


REFERENCE

Butt, A. M., Nasrullah, I., Tahir, S., & Tong, Y. (2012). Comparative Genomics Analysis of Mycobacterium ulcerans for the Identification of Putative Essential Genesand Therapeutic Candidates.pdf (p. 16). https://doi.org/10.1371/annotation/8ce51727-91b0-463f-9b4c-768aab0a230a