3-methyl-2-oxobutanoate hydroxymethyltransferase

GENE NAME

3-methyl-2-oxobutanoate hydroxymethyltransferase

ORGANISM

Mycobacterium ulcerans (strain Agy99)

GENE NAME

panB

GENE ID

4551392

TDR TARGET ID

952595

PROTEIN LENGTH

297

ASSOCIATED METABOLIC PATHWAYS

Pantothenate and CoA biosynthesis

FUNCTION

Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.

UNIPROT ID

A0PNG6

STRING

362242.MUL_1568

KEGG PATHWAY

mul:MUL_1568

GO - MOLECULAR FUNCTION

GO:0003864

GO:0046872

GO - BIOLOGICAL PROCESS

GO:0015940

LINK TO PUBMED


REFERENCE

Butt, A. M., Nasrullah, I., Tahir, S., & Tong, Y. (2012). Comparative Genomics Analysis of Mycobacterium ulcerans for the Identification of Putative Essential Genesand Therapeutic Candidates.pdf (p. 16). https://doi.org/10.1371/annotation/8ce51727-91b0-463f-9b4c-768aab0a230a