6,7-dimethyl-8-ribityllumazine synthase

GENE NAME

6,7-dimethyl-8-ribityllumazine synthase

ORGANISM

Mycobacterium ulcerans (strain Agy99)

GENE NAME

ribH

GENE ID

4551697

TDR TARGET ID

955374

PROTEIN LENGTH

160

ASSOCIATED METABOLIC PATHWAYS

Riboflavin metabolism

FUNCTION

Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

UNIPROT ID

A0PPL7

STRING

362242.MUL_1810

KEGG PATHWAY

mul:MUL_1810

GO - MOLECULAR FUNCTION

GO:0000906

GO - BIOLOGICAL PROCESS

GO:0009231

LINK TO PUBMED


REFERENCE

Butt, A. M., Nasrullah, I., Tahir, S., & Tong, Y. (2012). Comparative Genomics Analysis of Mycobacterium ulcerans for the Identification of Putative Essential Genesand Therapeutic Candidates.pdf (p. 16). https://doi.org/10.1371/annotation/8ce51727-91b0-463f-9b4c-768aab0a230a