GENE NAME
Thiazole synthase
ORGANISM
Mycobacterium ulcerans (strain Agy99)
GENE NAME
thiG
GENE ID
4552971
TDR TARGET ID
954829
PROTEIN LENGTH
264
ASSOCIATED METABOLIC PATHWAYS
Thiamine metabolism
FUNCTION
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H2S.
UNIPROT ID
A0PRX9
STRING
362242.MUL_2803
KEGG PATHWAY
mul:MUL_2803
GO - MOLECULAR FUNCTION
GO:1990107
GO - BIOLOGICAL PROCESS
GO:0009229
LINK TO PUBMED
https://pubmed.ncbi.nlm.nih.gov/22912793/
REFERENCE
Butt, A. M., Nasrullah, I., Tahir, S., & Tong, Y. (2012). Comparative Genomics Analysis of Mycobacterium ulcerans for the Identification of Putative Essential Genesand Therapeutic Candidates.pdf (p. 16). https://doi.org/10.1371/annotation/8ce51727-91b0-463f-9b4c-768aab0a230a