Tested Compounds

Tested Compounds	INHIBITORY CONCENTRATION VALUES (MIC/IC50)	Experimental Technique	2D structure	PubChem CID
Azythromycin	MIC = 0.39 µg/mL	in vitro & in vivo		53477736
Clarithromycin	MIC = 0.125 to 2 µg/mL	in vitro & in vivo		84029
Dapsone	MIC = 0.04 µg/mL to 5 µg/mL	in vitro & in vivo		2955
Clofazimine	MIC = 0.25 to 0.5 µg/ml	in vitro		2794
Rifampicin	MIC = 0.5 µ/ml	in vitro		135398735
Rifamycin	MIC = 0.06 to 0.125 µ/ml	in vitro		6324616
Aminoglycosides - streptomycin	MIC = 0.25 µg/ml	in vitro		19649
Ciprofloxacin	MIC = 1.15 µg/ml; 1–3 uM	in vitro		2764
Telacebec (Q203)	MIC = 15 or 7.5 ng/mL	in vitro & in vivo		68234908
TB47	MIC = 0.2 - 0.4µg/ml and > 50µg/ml	in vitro & in vivo		122188597
Diazene-1,2-dicarboxamides	MIC = 5.67–7.25 µg/ml	in vitro		5462814
Quinolinyl pyrimidines	MIC = Inactive	in vtro		692596
Pyrazolopyrimidines	MIC = 0.3–1.0 µM	in vtro		11636795
Aminopyrazoles	MIC = 0.3–1.0 µM	in vtro		74561
PA-824	MIC = 13.1 µg/ml	in vitro		456199
R207910	MIC = 0.03 µg/ml	in vitro		5388906
KRM-1648	MIC = 0.012 and 0.025 µg/ml	in vitro		135431094
SQ641	MIC = 8 µg/ml	in vitro		71589730
Diarylthiazoles	MIC = 1 - 3 µM, 3 - 10 µM, > 10 µM	in vitro
1,3-diaryltriazenes	IC50 = 2.82 and 0.06 µM	in vitro		8689
HMR 3004	MIC = 5 – 40 µg/ml	in vitro		5481603
HMR 3647	MIC = 5 – 40 µg/ml	in vitro		3002190
Moxidectin	MIC = 4 – 32 µg/ml	in vitro		9832912
Ivermectin	MIC = 4 – 32 µg/ml	in vitro		6321424
Selamectin	MIC = 2 – 4 µg/ml	in vitro		9578507
Linezolid	MIC = 3 – 10 µM; 0.73 µg/ml	in vitro		441401
Prulifloxacin	MIC = 1 – 3 µM	in vitro		65947
Sitafloxacin	MIC = 0.125 – 0.5 µg/ml	in vitro		461399
Moxifloxacin	MIC = 0.14 µg/ml	in vitro		152946
Sparfloxacin	MIC = 0.25 mg/l	in vitro		60464
Amikacin	MIC = 0.5 – 0.65 µg/ml	in vitro
ZINC38143792 (Euscaphic acid)	MIC = 50 µg mL−1	in silico		471426
ZINC95485880 ( hydroxy-(hydroxymethyl)-dimethyl-BLAHone)		in silico
ZINC95486305 ( [(E)-5-[(2S,8S,9S,10S,13S,14R,16R,17S)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-2,7,8,10,12)		in silico
ZINC000018185774 (luteolin)		in silico
ZINC000095485921 ( 1,4,8-trihydroxy-5-(3-methylbut-2-enyl)xanthen-9-one)		in silico
ZINC000014417338 (Alpinumisoflavone)		in silico		5490139
ZINC000005357841 ((6-methoxybenzo[1,3]dioxol-5-yl)BLAHone)		in silico		3781358 40529059
Phenothiazines	MIC = Inactive	in vitro		7108
hydroxyquinolones	MIC = 1 – 3 µM	in vitro		1923
GyrB_Pyrollamide PubChem_25223515	MIC = 0.3 – 1.0 µM	in vitro		25223515
GYRA-NTBI PubChem_15983305 2-oxo-1-[2-[4-[(3-oxo-4H-pyrido[3,2-b][1,4]oxazin-6-yl)methylamino]piperidin-1-yl]ethyl]quinoline-7-carbonitrile	MIC = Inactive	in vitro
GyrA_NTBI-analog	MIC = Inactive	in vitro
Ofloxacin	MIC = 1.26 – 2.0 µg/ml	in vitro		4583
Doxycycline	MIC = Inactive	in vitro		54671203
Rifapentine	MIC = 0.125 – 0.5 µg/ml	in vitro		135403821
Rifabutin	MIC = 0.1 – 0.4 µg/ml	in vitro		135398743
2,3,6-trihydroxymethyl benzoate (Sorindeia juglandifolia)	MIC = 62.5 µg/ml	in vitro
holadysamine (Holarrhena floribunda)	MIC = 50 µg/ml	in vitro		132602823
holaphyllinol (Holarrhena floribunda)	MIC = 125 µg/ml	in vitro		132602821
holamine or holaphyllamine (Holarrhena floribunda)	MIC = 125 µg/ml	in vitro		12310548